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AIDS Defining Conditions

The Centers for Disease Control and Prevention (CDC) defines an HIV+ person with a CD4 cell count of 200 or less as having AIDS. The CDC has also developed a list of more than 20 opportunistic infections (OIs) that are considered AIDS-defining conditions (see below). If you have HIV and one or more of these OIs, you have a diagnosis of AIDS.


This list comes from a government report and contains medical terms. If you have any questions, contact a treatment educator at a local AIDS service organization or call an AIDS information line such as the Project Inform National HIV/AIDS Treatment Hotline at 800-822-7422.


  • Candidiasis of bronchi, trachea, or lungs
  • Candidiasis, esophageal
  • Cervical cancer, invasive
  • Coccidioidomycosis, disseminated or extrapulmonary
  • Cryptococcosis, extrapulmonary
  • Cryptosporidiosis, chronic intestinal (greater than 1 month's duration)
  • Cytomegalovirus disease (other than liver, spleen, or nodes)
  • Cytomegalovirus retinitis (with loss of vision
  • Encephalopathy, HIV-related
  • Herpes simplex: chronic ulcer(s) (greater than 1 month's duration); or bronchitis, pneumonitis, or esophagitis
  • Histoplasmosis, disseminated or extrapulmonary
  • Isosporiasis, chronic intestinal (greater than 1 month's duration)
  • Kaposi's sarcoma
  • Lymphoma, Burkitt's (or equivalent term)
  • Lymphoma, immunoblastic (or equivalent term)
  • Lymphoma, primary, of brain
  • Mycobacterium avium complex or M. kansasii, disseminated or extrapulmonary
  • Mycobacterium tuberculosis, any site (pulmonary or extrapulmonary) Mycobacterium, other species or unidentified species, disseminated or extrapulmonary
  • Pneumocystis carinii pneumonia
  • Pneumonia, recurrent
  • Progressive multifocal leukoencephalopathy
  • Salmonella septicemia, recurrent
  • Toxoplasmosis of brain
  • Wasting syndrome due to HIV
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Information provided on this website is for educational purposes only. It is designed to support, not replace, personal medical care and should never be used as a substitute for personal medical attention, diagnosis, or hands-on treatment. We recommend all medical decisions be made in consultation with your personal health care provider.