Scientists see mechanism for spontaneous HIV 'cure'

November 4, 2014 - Paris - AFP

French scientists said Tuesday they had found the genetic mechanism by which two HIV-infected men may have experienced a "spontaneous cure", and said it offered a new strategy in the fight against AIDS.

Both men were infected by the human immunodeficiency virus (HIV), one of them 30 years ago, but never developed AIDS symptoms.

The AIDS-causing virus remained in their immune cells but was inactivated because its genetic code had been altered, the scientists said.

The change appeared to be linked to increased activity of a common enzyme named APOBEC, they theorised.

The "apparent spontaneous cure" throws up an intriguing avenue for drug engineers, the team said in a statement. Continue reading...

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