AIDS Defining Conditions

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The US Centers for Disease Control and Prevention (CDC) defines a person as having AIDS if she or he is living with HIV (HIV+) and has a CD4 cell count of 200 or less. The CDC has also developed a list of opportunistic infections (OIs), cancers, and conditions that are considered AIDS-defining conditions (see below). If you have HIV and one or more of these infections or conditions, you have a diagnosis of AIDS, no matter what your CD4 count is or how it changes in the future.

This list comes from a government report and contains medical terms. If you have any questions, contact a treatment educator at a local AIDS service organization or call an AIDS information line such as the Project Inform National HIV/AIDS Treatment Hotline at 800-822-7422. To find services across the world, visit AIDSmap's e-atlas.

  • Bacterial infections, multiple or recurrent (only for children less than 13 years old)
  • Candidiasis (type of yeast infection) of bronchi, trachea, or lungs
  • Candidiasis, esophageal
  • Cervical cancer, invasive (only among people 13 years old or older)
  • Coccidioidomycosis, disseminated or extrapulmonary
  • Cryptococcosis, extrapulmonary
  • Cryptosporidiosis, chronic intestinal (for longer than 1 month)
  • Cytomegalovirus disease (other than liver, spleen, or nodes), beginning when older than one month
  • Cytomegalovirus retinitis (with loss of vision)
  • Encephalopathy, HIV-related
  • Herpes simplex: chronic ulcers (lasting longer than 1 month); or bronchitis, pneumonitis, or esophagitis (beginning when older than one month)
  • Histoplasmosis, disseminated or extrapulmonary
  • Isosporiasis, chronic intestinal (for longer than 1 month)
  • Kaposi sarcoma
  • Lymphoid interstitial pneumonia or pulmonary lymphoid hyperplasia complex (only for children less than 13 years old)
  • Lymphoma, Burkitt (or equivalent term)
  • Lymphoma, immunoblastic (or equivalent term)
  • Lymphoma, primary, of brain
  • Mycobacterium avium complex or M. kansasii, disseminated or extrapulmonary
  • Mycobacterium tuberculosis, of any site, pulmonary (only among people 13 years old or older), disseminated, or extrapulmonary
  • Mycobacterium, other species or unidentified species, disseminated or extrapulmonary
  • Pneumocystis jirovecii pneumonia (PCP)
  • Pneumonia, recurrent (only among people 13 years old or older)
  • Progressive multifocal leukoencephalopathy
  • Salmonella septicemia, recurrent
  • Toxoplasmosis of brain, beginning when older than one month
  • Wasting syndrome due to HIV

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