Dr. Mack is the Medical Director for the St. Luke's Medical Group at 147th St and 8th Avenue in Harlem. Prior, she served as the associate medical director of the St. Luke's-Roosevelt Hospital Center for Comprehensive Care for seven years. She is a product of the Harlem community and has worked tirelessly to ensure Harlem residents receive quality medical attention. She was featured by the New York Daily News as "Dr. Angel" in 2011 and is an advocate for the underserved, providing quality care to patients who may not have previously had access to medical care. Dr. Mack treats high blood pressure, diabetes, chronic kidney disease, hepatitis, and HIV/AIDS. She has given lectures to consumer and physician audiences on a national stage. As described by one of her patients, she is "sensitive, caring, well informed, and professional." Dr. Mack is board certified in Internal Medicine, Nephrology, and HIV Medicine. Dr. Mack also serves on the Board of Directors of IRIS House.